Managing Hemochromatosis Through Blood Donations

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Course Objectives
  1. Identify the differences between hereditary and secondary hemochromatosis
  2. Discuss treatment options for hemochromatosis
  3. Assess the implications of hemochromatosis on blood donation practices and policies.
  4. Recognize the phlebotomist's role in managing hemochromatosis through blood donations

Course Content
Course Creator: Kristen Moylan BSPH, CCRC
Total CE Hours: 1 Credit Hour
Pace Course #: 586-2410-25

Course Description:
The purpose of this article is to explore both hereditary and secondary hemochromatosis and its implications on blood donations. This article will provide an overview of these conditions, discusses their treatment modalities, and will examine how they influence blood donation eligibility and practices.

References
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  2. Cleveland Clinic. (2021, January 1). Hemochromatosis (iron overload). Cleveland Clinic. https://my.clevelandclinic.org/health/diseases/14971-hemochromatosis-iron-overload
  3. Definition & Facts for Hemochromatosis | NIDDK. (2020, January). National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/liver-disease/hemochromatosis/definition-facts
  4. Hemochromatosis (Iron Overload): Causes, Symptoms, Treatment, Diet & More. (n.d.). Cleveland Clinic. https://my.clevelandclinic.org/health/diseases/14971-hemochromatosis-iron-overload#management-and-treatment
  5. Labcorp. (n.d.-a). 001123: Aspartate Aminotransferase (AST/SGOT) | LabCorp. Www.labcorp.com. https://www.labcorp.com/tests/001123/aspartate-aminotransferase-ast-sgot
  6. Labcorp. (n.d.-b). 001545: Alanine Aminotransferase (ALT/SGPT) | LabCorp. Www.labcorp.com. https://www.labcorp.com/tests/001545/alanine-aminotransferase-alt-sgpt
  7. Labcorp. (2025a). Ferritin. Labcorp.com. https://www.labcorp.com/tests/004598/ferritin#test-specimen
  8. Labcorp. (2025b). Transferrin. Labcorp.com. https://www.labcorp.com/tests/004937/transferrin#test-specimen
  9. Mayo Clinic. (2018). Hemochromatosis - Diagnosis and treatment - Mayo Clinic. Mayoclinic.org. https://www.mayoclinic.org/diseases-conditions/hemochromatosis/diagnosis-treatment/drc-20351448
  10. Mayo Clinic. (2023, January 6). Hemochromatosis - Symptoms and causes. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/hemochromatosis/symptoms-causes/syc-20351443
  11. Naser Mobarra, Mehrnoosh Shanaki, Ehteram, H., Nasiri, H., Mehdi Sahmani, Mohsen Saeidi, Goudarzi, M., Hoda Pourkarim, & Azad, M. (2016). A Review on Iron Chelators in Treatment of Iron Overload Syndromes. International Journal of Hematology-Oncology and Stem Cell Research, 10(4), 239. https://pmc.ncbi.nlm.nih.gov/articles/PMC5139945/
  12. NIDDK. (2020, January). Treatment of Hemochromatosis | NIDDK. National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/liver-disease/hemochromatosis/treatment
  13. Symptoms & Causes of Hemochromatosis | NIDDK. (2020, January). National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/liver-disease/hemochromatosis/symptoms-causes
  14. Table - PMC. (2016). Nih.gov. https://pmc.ncbi.nlm.nih.gov/articles/PMC5139945/table/T1/
  15. Transferrin Saturation Calculator. (2020). MDApp. https://www.mdapp.co/transferrin-saturation-calculator-444/
  16. Yates, A. (2024, August 17). Essential Information for Understanding Therapeutic Phlebotomy. Verywell Health. https://www.verywellhealth.com/what-is-therapeutic-phlebotomy-4058459
  17. Zubair, A. (2014). Therapeutic phlebotomy. Clinical Liver Disease, 4(5), 102–106. https://doi.org/10.1002/cld.408
  18. (2025). Aafp.org. https://www.aafp.org/pubs/afp/issues/2021/0900/p263/jcr:content/root/aafp-article-primary-content-container/aafp_article_main_par/aafp_figure.enlarge.html
  19. American Red Cross. (n.d.). Eligibility Criteria Alphabetical Listing. Www.redcrossblood.org. https://www.redcrossblood.org/donate-blood/how-to-donate/eligibility-requirements/eligibility-criteria-alphabetical.html
  20. American Red Cross. (n.d.-b). Frequently Asked Questions. Www.redcrossblood.org. Retrieved June 18, 2025, from https://www.redcrossblood.org/faq.html#eligibility
  21. Jenna Communications. (2022, August 1). The American Red Cross is Now Accepting Hemochromatosis Donors After Not Accepting Them for Years - Jenna Communications. Jenna Communications. https://jennacommunications.com/the-american-red-cross-is-now-accepting-hemochromatosis-donors-after-not-accepting-them-for-years/

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